PS181. A study of hippocampal volumes in first-episode, drug-naïve major depression disorder.
نویسندگان
چکیده
s | 65 PS179 A depressive patient who achieved remission by escitalopram: cerebral blood flow variation during pleasant/unpleasant image tasks. Yoshihisa Shoji, Masayuki Inoue, Youhei Ishii, Yusuke Kato, Kiichiro Morita, Naohisa Uchimira, Yuki Yamashita, Hiroko Yanagimoto Cognitive and Molecular Research Institute of Brain Diseases, Kurume
منابع مشابه
Life events and hippocampal volume in first-episode major depression.
BACKGROUND There are many studies on life events in depression and also several studies examining brain structural changes in the hippocampus of depressed patients. However, only few studies have focused on the association of life events and hippocampal volume in depression. The hypothesis of a significant negative association between life events and hippocampal volumes in first episode depress...
متن کاملHippocampal volume in first episode and recurrent depression.
Abnormalities in limbic-thalamic-cortical networks are hypothesized to modulate human mood states. In the present study differences in hippocampal volumes of patients with a first episode of depression, recurrent major depression and healthy control subjects were examined with high-resolution magnetic resonance imaging (MRI). Male patients with a first episode of major depression had a signific...
متن کاملHippocampal changes in patients with a first episode of major depression.
OBJECTIVE Previous work suggests that patients with unipolar depression may have structural as well as functional abnormalities in limbic-thalamic-cortical networks, which are hypothesized to modulate human mood states. A core area in these networks is the hippocampus. In the present study, differences in volumes of hippocampal gray and white matter between patients with a first episode of majo...
متن کاملEffect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study.
OBJECTIVE According to the stress-toxicity hypothesis of depression, hippocampal volumes may diminish as the disease progresses. We sought to examine the changes in hippocampal and amygdala volumes at baseline and at 3 years after an acute depressive episode, and the impact of reduced hippocampal volumes on the outcome. METHODS In a prospective, longitudinal study, we examined the hippocampus...
متن کاملCourse of illness, hippocampal function, and hippocampal volume in major depression.
Studies have examined hippocampal function and volume in depressed subjects, but none have systematically compared never-treated first-episode patients with those who have had multiple episodes. We sought to compare hippocampal function, as assessed by performance on hippocampal-dependent recollection memory tests, and hippocampal volumes, as measured in a 1.5-T magnetic resonance imager, in de...
متن کامل